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In the field of genomics, by analyzing key information such as individual-specific target variations, mutation loads, complex mutation characteristics, and tumor-specific antigens, a solid theoretical foundation has been laid for the three pillars of precision medicine—targeted therapy, immune checkpoint inhibitors, and personalized anticancer vaccines (Miao and Van Allen, 2016

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As the American Society of Health-System Pharmacists puts it in its guide to assigning beyond-use dates: "Ultimately the assigned BUD should default to the more conservative dating after an assessment of sterility and stability." Stability is the peptide chemistry